Research During my graduate research with Dr John Tyson, I built mathematical models to understand dynamical aspects:
Modeling the START transition in the budding yeast cell cycle:
Built a detailed mathematical model (~100 ODEs, ~150 parameters) for the START transition in yeast and integrated it with our published model of the whole cell cycle. Model addresses outstanding issues related to the precise mechanism and timing of transcriptional, post- translational and localization events, as well as size control under varying growth conditions.